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Last Close
Feb 13  •  04:00PM ET
124.12
Dollar change
+1.02
Percentage change
0.83
%
Feb 12, 2:41 PMNeurocrine Biosciences shares fall over 10% after a softer-than-expected 2026 INGREZZA sales outlook of $2.7–$2.8B (~10% growth), as Q4 2025 EPS of $1.88 missed the $2.25 consensus despite a 2.9% revenue beat and 22% growth (Q4 net product sales $798.3M; FY $2.83B). On the call, management said CRENESSITY generated over $300M in 2025 sales with ~10% CAH penetration, withheld 2026 guidance and flagged an ~5% Q1 gross-to-net headwind, while Needham, HC Wainwright, Wedbush and BMO maintained positive ratings with modest price target cuts.
Index- P/E26.59 EPS (ttm)4.67 Insider Own2.67% Shs Outstand100.10M Perf Week-12.10%
Market Cap12.46B Forward P/E16.34 EPS next Y7.60 Insider Trans-3.66% Shs Float97.05M Perf Month-8.28%
Enterprise Value11.45B PEG0.59 EPS next Q1.11 Inst Own99.64% Short Float3.44% Perf Quarter-15.48%
Income478.60M P/S4.35 EPS this Y28.53% Inst Trans0.21% Short Ratio3.09 Perf Half Y-5.48%
Sales2.86B P/B3.82 EPS next Y26.56% ROA11.13% Short Interest3.34M Perf YTD-12.49%
Book/sh32.50 P/C8.41 EPS next 5Y27.85% ROE16.38% 52W High160.18 -22.51% Perf Year6.20%
Cash/sh14.75 P/FCF16.64 EPS past 3/5Y44.05% 2.31% ROIC13.05% 52W Low84.23 47.36% Perf 3Y19.90%
Dividend Est.- EV/EBITDA17.17 Sales past 3/5Y24.32% 22.29% Gross Margin98.18% Volatility4.44% 3.12% Perf 5Y8.78%
Dividend TTM- EV/Sales4.00 EPS Y/Y TTM41.73% Oper. Margin22.25% ATR (14)4.60 Perf 10Y244.40%
Dividend Ex-Date- Quick Ratio3.30 Sales Y/Y TTM21.45% Profit Margin16.73% RSI (14)30.92 Recom1.38
Dividend Gr. 3/5Y- - Current Ratio3.39 EPS Q/Q47.94% SMA20-8.35% Beta0.34 Target Price178.37
Payout0.00% Debt/Eq0.14 Sales Q/Q28.33% SMA50-11.94% Rel Volume1.96 Prev Close123.10
Employees2000 LT Debt/Eq0.13 EarningsFeb 11 AMC SMA200-8.49% Avg Volume1.08M Price124.12
IPOMay 23, 1996 Option/ShortYes / Yes EPS/Sales Surpr.-17.97% 1.90% Trades Volume2,122,668 Change0.83%
Date Action Analyst Rating Change Price Target Change
Jan-08-26Downgrade Morgan Stanley Overweight → Equal-Weight $175
Oct-21-25Initiated Citigroup Buy $175
Jul-21-25Initiated Truist Buy $163
Jul-10-25Initiated Goldman Buy $182
Apr-15-25Upgrade Needham Hold → Buy $138
Apr-14-25Upgrade RBC Capital Mkts Sector Perform → Outperform $137
Feb-11-25Initiated Deutsche Bank Hold $138
Oct-10-24Resumed Raymond James Outperform $155
Aug-29-24Upgrade Piper Sandler Neutral → Overweight $131 → $159
Apr-24-24Upgrade Wells Fargo Equal Weight → Overweight $140 → $170
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Neurocrine Biosciences, Inc. is a neuroscience-focused, biopharmaceutical company, which engages in the research and development, commercialization, and sale of pharmaceuticals for the treatment of neurological, neuroendocrine, and neuropsychiatric disorders. Its portfolio of products includes treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia (CAH), and endometriosis and uterine fibroids. The company was founded by Kevin C. Gorman and Wylie W. Vale in January 1992 and is headquartered in San Diego, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Boyer David W.Chief Corp. Affairs OfficerJan 31 '26Option Exercise0.002,09605,902Feb 03 06:22 PM
BENEVICH ERICChief Commercial OfficerJan 31 '26Option Exercise0.002,294054,047Feb 03 06:21 PM
ABERNETHY MATTChief Financial OfficerJan 31 '26Option Exercise0.002,437038,465Feb 03 06:06 PM
Cooke JulieChief Human Resources OfficerJan 31 '26Option Exercise0.001,741028,599Feb 03 06:05 PM
Delaet IngridChief Regulatory OfficerJan 31 '26Option Exercise0.0080105,531Feb 03 06:04 PM
Gano KyleChief Executive OfficerJan 31 '26Option Exercise0.002,9270143,334Feb 03 06:03 PM
GORMAN KEVIN CHARLESDirectorJan 31 '26Option Exercise0.005,1420519,738Feb 03 06:02 PM
Lippoldt DarinChief Legal OfficerJan 31 '26Option Exercise0.002,373049,127Feb 03 06:01 PM
Onyia JudeChief Scientific OfficerJan 31 '26Option Exercise0.00238016,119Feb 03 06:01 PM
Gano KyleChief Executive OfficerJan 16 '26Option Exercise35.9936,4001,310,036174,995Jan 20 06:56 PM
Gano KyleChief Executive OfficerJan 16 '26Sale132.7036,4004,830,458140,407Jan 20 06:56 PM
KYLE GANOOfficerJan 16 '26Proposed Sale133.3536,4004,853,940Jan 16 04:21 PM
Lippoldt DarinChief Legal OfficerJan 08 '26Option Exercise35.993,349120,53146,754Jan 12 04:18 PM
Norwalk Leslie VDirectorDec 15 '25Option Exercise91.0710,000910,74212,429Dec 17 04:24 PM
Norwalk Leslie VDirectorDec 15 '25Sale152.235,000761,1447,429Dec 17 04:24 PM
Norwalk Leslie VDirectorDec 16 '25Sale155.091,190184,5586,239Dec 17 04:24 PM
Norwalk Leslie VDirectorDec 15 '25Proposed Sale155.1111,2501,745,000Dec 15 10:58 AM
Lippoldt DarinChief Legal OfficerDec 08 '25Option Exercise43.244,376189,21847,781Dec 10 09:04 AM
Lippoldt DarinChief Legal OfficerDec 08 '25Sale159.654,376698,61543,405Dec 10 09:04 AM
DARIN LIPPOLDTOfficerDec 08 '25Proposed Sale155.514,376680,512Dec 08 04:35 PM
LYONS GARY ADirectorDec 03 '25Option Exercise47.8915,000718,350135,482Dec 04 04:14 PM
LYONS GARY ADirectorDec 03 '25Sale152.6115,0002,289,082120,482Dec 04 04:14 PM
GARY A LYONS REVOCABLE LIVING DirectorDec 03 '25Proposed Sale152.4815,0002,287,200Dec 03 04:36 PM
BENEVICH ERICChief Commercial OfficerNov 28 '25Option Exercise35.995,970214,86050,863Dec 02 05:21 PM
BENEVICH ERICChief Commercial OfficerNov 28 '25Sale151.745,970905,88144,893Dec 02 05:21 PM
Onyia JudeChief Scientific OfficerNov 29 '25Option Exercise0.004,426018,129Dec 02 05:14 PM
ERIC BENEVICHOfficerNov 28 '25Proposed Sale151.585,970904,933Nov 28 01:20 PM
MORROW GEORGE JDirectorNov 25 '25Option Exercise47.8915,000718,35022,068Nov 26 04:28 PM
MORROW GEORGE JDirectorNov 25 '25Sale143.3715,0002,150,5127,068Nov 26 04:28 PM
GEORGE MORROWDirectorNov 25 '25Proposed Sale141.2515,0002,118,750Nov 25 04:25 PM
RASTETTER WILLIAM HDirectorNov 05 '25Option Exercise47.8918,000862,02058,360Nov 06 05:25 PM
RASTETTER WILLIAM HDirectorNov 05 '25Sale151.8218,0002,732,69040,360Nov 06 05:25 PM
Gano KyleOfficerNov 04 '25Proposed Sale141.9730042,591Nov 05 09:09 PM
WILLIAM H. RASTETTERDirectorNov 05 '25Proposed Sale143.1918,0002,577,420Nov 05 04:19 PM
Gano KyleChief Executive OfficerNov 01 '25Option Exercise0.006130140,720Nov 04 08:18 PM
Gano KyleChief Executive OfficerNov 04 '25Sale141.9730042,591140,407Nov 04 08:18 PM
GORMAN KEVIN CHARLESDirectorAug 07 '25Option Exercise35.99106,3223,826,529620,918Aug 11 04:55 PM
GORMAN KEVIN CHARLESDirectorAug 07 '25Sale126.41106,32213,440,281514,596Aug 11 04:55 PM
KEVIN CHARLES GORMANDirectorAug 07 '25Proposed Sale128.43106,32213,654,934Aug 07 04:24 PM
Delaet IngridChief Regulatory OfficerJul 10 '25Option Exercise79.0245736,1125,187Jul 11 05:15 PM
Delaet IngridChief Regulatory OfficerJul 10 '25Sale135.0045761,6954,730Jul 11 05:15 PM
Onyia JudeChief Scientific OfficerJul 09 '25Option Exercise84.7459,8195,069,06278,108Jul 11 05:01 PM
Onyia JudeChief Scientific OfficerJul 09 '25Sale130.4659,8197,803,68818,289Jul 11 05:01 PM
INGRID DELAETOfficerJul 10 '25Proposed Sale133.5145761,014Jul 10 04:32 PM
Onyia JudeChief Scientific OfficerJul 02 '25Option Exercise84.7420,3621,725,47638,651Jul 07 04:10 PM
Onyia JudeChief Scientific OfficerJul 02 '25Sale130.1320,3622,649,73818,289Jul 07 04:10 PM
JUDE ONYIAOfficerJul 02 '25Proposed Sale128.0080,18110,263,168Jul 02 04:22 PM
GORMAN KEVIN CHARLESDirectorMay 27 '25Sale120.389,6131,157,211514,596May 29 06:15 PM
KEVIN CHARLES GORMANDirectorMay 27 '25Proposed Sale120.189,6131,155,290May 27 04:38 PM
RASTETTER WILLIAM HDirectorMay 22 '25Option Exercise0.002,869040,360May 22 06:15 PM
POON CHRISTINE ADirectorMay 22 '25Option Exercise0.001,43501,435May 22 05:32 PM
Sharp ShaliniDirectorMay 22 '25Option Exercise0.001,43502,429May 22 05:28 PM
SHERWIN STEPHEN ADirectorMay 22 '25Option Exercise0.002,869013,542May 22 05:26 PM
POPS RICHARD FDirectorMay 22 '25Option Exercise0.002,869034,480May 22 05:23 PM
MORROW GEORGE JDirectorMay 22 '25Option Exercise0.002,86907,068May 22 05:20 PM
LYONS GARY ADirectorMay 22 '25Option Exercise0.001,4350120,482May 22 05:18 PM
Norwalk Leslie VDirectorMay 22 '25Option Exercise0.001,43502,429May 22 05:14 PM
Mercier JohannaDirectorMay 22 '25Option Exercise0.001,43503,535May 22 05:12 PM
Cooke JulieChief Human Resources OfficerMay 16 '25Option Exercise61.826,468399,85226,858May 20 04:43 PM
RASTETTER WILLIAM HDirectorMay 05 '25Option Exercise42.7630,0001,282,80067,491May 07 07:05 PM
RASTETTER WILLIAM HDirectorMay 05 '25Sale110.2030,0003,305,95237,491May 07 07:05 PM
WILLIAM H. RASTETTEROfficerMay 05 '25Proposed Sale109.6830,0003,290,400May 05 04:40 PM
ROBERTS EIRYChief Medical OfficerFeb 14 '25Sale115.0450057,52135,640Feb 14 06:42 PM
EIRY WYN ROBERTSOfficerFeb 14 '25Proposed Sale115.0450057,521Feb 14 04:12 PM