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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 28 | Sale | 10.24 | 6,226 | 63,739 | 898,131 | Mar 02 03:20 PM |
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 28 | Sale | 10.24 | 6,226 | 63,739 | 713,757 | Mar 02 03:20 PM |
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 17 | Sale | 12.12 | 9,088 | 110,177 | 904,357 | Feb 22 04:15 PM |
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 17 | Sale | 12.12 | 9,079 | 110,068 | 698,983 | Feb 22 04:15 PM |
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 07 | Sale | 9.86 | 6,707 | 66,144 | 913,445 | Feb 09 05:22 PM |
| KPTI | Shacham Sharon | Chief Scientific Officer | Feb 07 | Sale | 9.86 | 6,764 | 66,707 | 708,062 | Feb 09 05:22 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 18 | Sale | 12.39 | 4,000 | 49,553 | 714,826 | Mar 23 07:50 AM |
| KPTI | Shacham Sharon | President & CSO | Feb 18 | Sale | 14.83 | 9,495 | 140,822 | 776,452 | Feb 22 08:10 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 18 | Sale | 14.83 | 9,495 | 140,822 | 575,126 | Feb 22 08:10 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 11 | Sale | 15.52 | 6,642 | 103,077 | 764,147 | Feb 17 06:45 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 11 | Sale | 15.52 | 6,601 | 102,441 | 562,821 | Feb 17 06:45 PM |
| KPTI | Shacham Sharon | President & CSO | Oct 12 | Option Exercise | 0.03 | 7,500 | 248 | 763,989 | Oct 14 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Oct 12 | Sale | 14.89 | 7,500 | 111,682 | 756,489 | Oct 14 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 17 | Option Exercise | 0.03 | 1,477 | 49 | 757,966 | Aug 18 06:05 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 17 | Sale | 15.00 | 1,477 | 22,155 | 756,489 | Aug 18 06:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 15 | Option Exercise | 0.03 | 7,500 | 248 | 763,989 | Jul 17 04:24 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 15 | Sale | 19.43 | 7,500 | 145,723 | 756,489 | Jul 17 04:24 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 09 | Option Exercise | 4.75 | 7,500 | 35,640 | 763,989 | Jul 13 06:43 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 10 | Option Exercise | 4.75 | 7,500 | 35,640 | 562,622 | Jul 13 06:43 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 10 | Sale | 19.01 | 7,500 | 142,539 | 555,122 | Jul 13 06:43 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 09 | Sale | 19.53 | 7,500 | 146,487 | 756,489 | Jul 13 06:43 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 22 | Option Exercise | 0.03 | 7,500 | 248 | 763,989 | Jun 24 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 22 | Sale | 20.00 | 7,500 | 150,000 | 756,489 | Jun 24 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 15 | Option Exercise | 0.03 | 7,500 | 248 | 763,632 | Jun 17 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 15 | Sale | 16.37 | 7,500 | 122,779 | 756,489 | Jun 17 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 09 | Option Exercise | 4.75 | 7,500 | 35,640 | 763,989 | Jun 11 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 10 | Option Exercise | 4.75 | 7,500 | 35,640 | 562,622 | Jun 11 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 10 | Sale | 18.13 | 7,500 | 135,944 | 555,122 | Jun 11 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 09 | Sale | 18.50 | 7,500 | 138,746 | 756,489 | Jun 11 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | May 15 | Option Exercise | 0.03 | 7,500 | 248 | 763,989 | May 19 05:34 PM |
| KPTI | Shacham Sharon | President & CSO | May 18 | Option Exercise | 0.03 | 7,500 | 248 | 763,989 | May 19 05:34 PM |
| KPTI | Shacham Sharon | President & CSO | May 18 | Sale | 20.00 | 7,500 | 150,000 | 756,489 | May 19 05:34 PM |
| KPTI | Shacham Sharon | President & CSO | May 15 | Sale | 18.65 | 7,500 | 139,840 | 756,489 | May 19 05:34 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Option Exercise | 4.75 | 7,500 | 35,640 | 763,989 | May 11 04:22 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Option Exercise | 4.75 | 7,500 | 35,640 | 562,622 | May 11 04:22 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Sale | 19.63 | 7,500 | 147,205 | 756,489 | May 11 04:22 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Sale | 19.63 | 7,500 | 147,209 | 555,122 | May 11 04:22 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 08 | Option Exercise | 4.75 | 10,000 | 47,520 | 766,489 | Apr 10 05:06 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 09 | Option Exercise | 4.75 | 10,000 | 47,520 | 565,122 | Apr 10 05:06 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 09 | Sale | 20.64 | 10,000 | 206,404 | 555,122 | Apr 10 05:06 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 08 | Sale | 18.61 | 10,000 | 186,115 | 756,489 | Apr 10 05:06 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 09 | Option Exercise | 4.75 | 10,000 | 47,520 | 766,489 | Mar 11 07:10 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 10 | Option Exercise | 4.75 | 10,000 | 47,520 | 565,122 | Mar 11 07:10 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 10 | Sale | 22.22 | 10,000 | 222,186 | 555,122 | Mar 11 07:10 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 09 | Sale | 22.52 | 10,000 | 225,195 | 756,489 | Mar 11 07:10 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 19 | Sale | 16.48 | 8,817 | 145,321 | 756,489 | Feb 21 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 19 | Sale | 16.48 | 8,817 | 145,321 | 555,122 | Feb 21 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 10 | Option Exercise | 4.75 | 10,000 | 47,520 | 753,506 | Feb 12 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 11 | Option Exercise | 4.75 | 10,000 | 47,520 | 552,139 | Feb 12 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 11 | Sale | 17.43 | 10,000 | 174,294 | 542,139 | Feb 12 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 10 | Sale | 16.93 | 10,000 | 169,327 | 743,506 | Feb 12 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 08 | Option Exercise | 4.75 | 10,000 | 47,520 | 753,506 | Jan 10 05:04 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 09 | Option Exercise | 4.75 | 10,000 | 47,520 | 552,139 | Jan 10 05:04 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 09 | Sale | 19.19 | 10,000 | 191,880 | 542,139 | Jan 10 05:04 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 08 | Sale | 18.57 | 10,000 | 185,705 | 743,506 | Jan 10 05:04 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 10 | Option Exercise | 4.75 | 10,000 | 47,520 | 539,767 | Dec 11 05:21 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 09 | Option Exercise | 4.75 | 10,000 | 47,520 | 741,134 | Dec 11 05:21 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 09 | Sale | 17.02 | 10,000 | 170,210 | 731,134 | Dec 11 05:21 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 10 | Sale | 15.99 | 10,000 | 159,896 | 529,767 | Dec 11 05:21 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 08 | Option Exercise | 4.75 | 10,000 | 47,520 | 741,134 | Nov 12 04:34 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 11 | Option Exercise | 4.75 | 10,000 | 47,520 | 539,767 | Nov 12 04:34 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 11 | Sale | 14.76 | 10,000 | 147,610 | 529,767 | Nov 12 04:34 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 08 | Sale | 14.63 | 10,000 | 146,254 | 731,134 | Nov 12 04:34 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 01 | Option Exercise | 4.75 | 10,000 | 47,520 | 741,134 | Nov 05 04:10 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 01 | Option Exercise | 4.75 | 10,000 | 47,520 | 539,767 | Nov 05 04:10 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 01 | Sale | 12.00 | 10,000 | 120,000 | 731,134 | Nov 05 04:10 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 01 | Sale | 12.00 | 10,000 | 120,000 | 529,767 | Nov 05 04:10 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 16 | Option Exercise | 4.75 | 10,000 | 47,520 | 741,134 | Sep 17 04:54 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 16 | Option Exercise | 4.75 | 10,000 | 47,520 | 539,767 | Sep 17 04:54 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 16 | Sale | 12.00 | 10,000 | 120,000 | 731,134 | Sep 17 04:54 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 16 | Sale | 12.00 | 10,000 | 120,000 | 529,767 | Sep 17 04:54 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 07 | Option Exercise | 0.03 | 12,500 | 412 | 743,634 | Jan 09 04:37 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 07 | Sale | 10.23 | 12,500 | 127,824 | 731,134 | Jan 09 04:37 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 07 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Dec 10 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 07 | Sale | 10.11 | 12,500 | 126,422 | 713,510 | Dec 10 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 26 | Option Exercise | 4.75 | 9,600 | 45,619 | 521,743 | Nov 27 04:20 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 26 | Sale | 11.00 | 9,600 | 105,600 | 512,143 | Nov 27 04:20 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 19 | Option Exercise | 4.75 | 400 | 1,901 | 512,543 | Nov 21 08:03 AM |
| KPTI | Shacham Sharon | President & CSO | Nov 19 | Sale | 11.14 | 400 | 4,455 | 512,143 | Nov 21 08:03 AM |
| KPTI | Shacham Sharon | President & CSO | Nov 07 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Nov 09 04:16 PM |
| KPTI | Shacham Sharon | President & CSO | Nov 07 | Sale | 11.65 | 12,500 | 145,592 | 713,510 | Nov 09 04:16 PM |
| KPTI | Shacham Sharon | President & CSO | Oct 18 | Option Exercise | 4.75 | 10,000 | 47,520 | 522,143 | Oct 22 04:09 PM |
| KPTI | Shacham Sharon | President & CSO | Oct 18 | Sale | 12.63 | 10,000 | 126,304 | 512,143 | Oct 22 04:09 PM |
| KPTI | Shacham Sharon | President & CSO | Oct 08 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Oct 09 08:00 AM |
| KPTI | Shacham Sharon | President & CSO | Oct 08 | Sale | 15.75 | 12,500 | 196,832 | 713,510 | Oct 09 08:00 AM |
| KPTI | Shacham Sharon | President & CSO | Sep 18 | Option Exercise | 4.75 | 10,000 | 47,520 | 522,143 | Sep 18 05:26 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 18 | Sale | 18.26 | 10,000 | 182,615 | 512,143 | Sep 18 05:26 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 07 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Sep 10 04:11 PM |
| KPTI | Shacham Sharon | President & CSO | Sep 07 | Sale | 19.31 | 12,500 | 241,384 | 713,510 | Sep 10 04:11 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 20 | Option Exercise | 4.75 | 10,000 | 47,520 | 522,143 | Aug 21 04:14 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 20 | Sale | 17.46 | 10,000 | 174,568 | 512,143 | Aug 21 04:14 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 07 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Aug 08 04:04 PM |
| KPTI | Shacham Sharon | President & CSO | Aug 07 | Sale | 18.04 | 12,500 | 225,556 | 713,510 | Aug 08 04:04 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 18 | Option Exercise | 2.17 | 10,000 | 21,678 | 522,143 | Jul 20 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 18 | Sale | 18.27 | 10,000 | 182,686 | 512,143 | Jul 20 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 09 | Option Exercise | 0.03 | 12,500 | 412 | 726,010 | Jul 10 04:09 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 09 | Sale | 18.72 | 12,500 | 233,990 | 713,510 | Jul 10 04:09 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 18 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Jun 19 04:06 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 18 | Sale | 18.66 | 10,000 | 186,558 | 512,143 | Jun 19 04:06 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 07 | Option Exercise | 0.26 | 10,000 | 2,570 | 723,510 | Jun 11 04:11 PM |
| KPTI | Shacham Sharon | President & CSO | Jun 07 | Sale | 17.30 | 10,000 | 172,991 | 713,510 | Jun 11 04:11 PM |
| KPTI | Shacham Sharon | President & CSO | May 18 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | May 21 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | May 18 | Sale | 19.39 | 10,000 | 193,870 | 512,143 | May 21 04:28 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | May 08 04:19 PM |
| KPTI | Shacham Sharon | President & CSO | May 07 | Sale | 16.77 | 10,000 | 167,747 | 713,510 | May 08 04:19 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 18 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Apr 20 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 18 | Sale | 14.79 | 10,000 | 147,878 | 512,143 | Apr 20 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 09 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | Apr 10 04:17 PM |
| KPTI | Shacham Sharon | President & CSO | Apr 09 | Sale | 12.48 | 10,000 | 124,829 | 713,510 | Apr 10 04:17 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 19 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Mar 20 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 19 | Sale | 15.29 | 10,000 | 152,895 | 512,143 | Mar 20 04:36 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 07 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | Mar 08 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Mar 07 | Sale | 16.15 | 10,000 | 161,463 | 713,510 | Mar 08 05:54 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 20 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Feb 22 04:17 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 20 | Sale | 14.79 | 10,000 | 147,872 | 512,143 | Feb 22 04:17 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 07 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | Feb 08 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Feb 07 | Sale | 12.50 | 10,000 | 125,048 | 713,510 | Feb 08 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 18 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Jan 22 04:08 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 18 | Sale | 10.09 | 10,000 | 100,882 | 512,143 | Jan 22 04:08 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 08 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | Jan 09 04:08 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 08 | Sale | 10.08 | 10,000 | 100,769 | 713,510 | Jan 09 04:08 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 18 | Option Exercise | 0.26 | 10,000 | 2,640 | 522,143 | Dec 20 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 18 | Sale | 9.16 | 10,000 | 91,553 | 512,143 | Dec 20 04:21 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 07 | Option Exercise | 0.26 | 10,000 | 2,640 | 723,510 | Dec 08 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Dec 07 | Sale | 10.39 | 10,000 | 103,903 | 713,510 | Dec 08 04:05 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 12 | Sale | 33.00 | 25,000 | 825,000 | 763,963 | Jan 14 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Jan 12 | Sale | 33.00 | 25,000 | 825,000 | 562,596 | Jan 14 04:07 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 02 | Sale | 42.50 | 100,000 | 4,250,000 | 808,963 | Jul 02 06:12 PM |
| KPTI | Shacham Sharon | President & CSO | Jul 02 | Sale | 42.50 | 100,000 | 4,250,000 | 587,596 | Jul 02 06:12 PM |
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